Proyecto que refleja la esperanza de preservar al rinoceronte blanco

Gracias a embriones híbridos del rinoceronte blanco del norte, (animal que está en camino inminente de extinción luego de la muerte de Sudán, el último macho en su especie) se podría preservar la vida de estos animales en la tierra.

El informe de la revista Nature Communication detalló que se hizo una mezcla con embriones de una subespecie relacionada al rinoceronte blanco y se creó mediante tecnologías de reproducción asistida dentro de un laboratorio. Además, es el primer embrión híbrido creado a través de fecundación “in vitro” que alcanza la etapa de blastocisto -con 5 o 6 días de desarrollo- con una estructura celular compleja.

El experimento podría preservar al mamífero, cuyo último macho falleció el marzo pasado, por lo que ahora solo sobreviven dos hembras en Kenia.

Todo el proyecto comenzó con la recolección de numerosos ovocitos, que es la célula germinal femenina de ejemplares del mamífero, tanto de la subespecie de rinoceronte blanco del norte como del sur, gracias a un aparato de casi dos metros de largo de implantación transrectal.

El proyecto es liderado por Thomas Hildebrandt, del Instituto Leibniz de Investigación para Zoológicos y Vida Salvaje, en Alemania. Además, se inspiró en la investigación ganadora del Nobel de Fisiología o Medicina de 2012, de Shinya Yamanaka, que descubrió que las células maduras se pueden reprogramar para convertirse en pluripotentes, permitió un nuevo enfoque al combinar las “tecnologías de reproducción asistida con la recolección de ovocitos”

Los científicos obtuvieron esperma descongelado de machos del rinoceronte en peligro y fertilizaron ovocitos de la subespecie más cercana, el blanco del sur, mediante inyección intracitoplásmica de esperma.

Los embriones híbridos resultantes se desarrollaron hasta la etapa de blastocisto y se congelaron para una posible implantación en hembras de la subespecie del sur en algún momento en el futuro.

Un próximo paso será trasladarse a Kenia para recoger ovocitos de las dos féminas restantes del norte y crear nuevos blastocistos donde tanto el óvulo como el esperma sean de la misma subespecie.

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